发明名称 |
Generation of hematopoietic cells from multipotent neural stem cells |
摘要 |
Multipotent neural stem cell (MNSC) progeny are induced to generate cells of the hematopoietic system by placing the MNSC progeny in a hematopoietic-inducing environment. The hematopoietic-inducing environment can be either ex vivo or in vivo. A mammal's circulatory system provides an in vivo environment that can induce xenogeneic, allogeneic, or autologous MNSC progeny to generate a full complement of hematopoietic cells. Transplantation of MNSC progeny provides an alternative to bone marrow and hematopoietic stem cell transplantation to treat blood-related disorders.
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申请公布号 |
US6093531(A) |
申请公布日期 |
2000.07.25 |
申请号 |
US19980100679 |
申请日期 |
1998.06.19 |
申请人 |
NEUROSPHERES HOLDINGS LTD. |
发明人 |
BJORNSON, CHRISTOPHER R.;RIETZE, ROD L.;REYNOLDS, BRENT A.;VESCOVI, ANGELO L. |
分类号 |
A61K35/12;A61K35/14;A61K35/30;A61K48/00;A61P7/00;A61P7/06;C12N5/0797;(IPC1-7):C12N5/06 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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