GENETIC IMMUNIZATION WITH CO-DELIVERY OF NUCLEIC ACID AND CYTOKINES
摘要
Nucleic acids encoding antigens can be delivered to mammals to induce immunity to the encoded antigens. The expression of the encoded antigens in the mammal induces an immune response to the antigen. Furthermore, co-delivery of an encapsulated cytokine in a microsphere enhances the immune response. Selection of cytokines can be used to manipulate the type of immune response which is induced.
申请公布号
WO0041679(A1)
申请公布日期
2000.07.20
申请号
WO2000US00730
申请日期
2000.01.13
申请人
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;LIU, SHU, QUIN;SONG, RUIJIANG;AUGUST, J., THOMAS;LEONG, KAM, W.
发明人
LIU, SHU, QUIN;SONG, RUIJIANG;AUGUST, J., THOMAS;LEONG, KAM, W.