发明名称 |
99mTc MARKIERTE LIPOSOMEN |
摘要 |
The invention relates to the efficient preparation of radionuclide labeled liposomes and radionuclide-labeled liposome-encapsulated protein. In particular, a 99mTc carrier is used to label preformed liposomes or liposome-encapsulated hemoglobin. 99mTc-labeled liposomes and liposome-encapsulated 99mTc labeled hemoglobin are highly stable in vitro and in vivo and are suitable for a variety of clinical uses, including biodistribution imaging studies. The invention also relates to a method of labeling neutrophils using 99mtechnetium-labeled liposomes or liposome-encapsulated hemoglobin. A kit method useful for the convenient preparation of 99mTc-labeled liposomes or liposome-encapsulated hemoglobin for clinical use is also disclosed. |
申请公布号 |
DE69131881(T2) |
申请公布日期 |
2000.07.20 |
申请号 |
DE1991631881T |
申请日期 |
1991.05.30 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
PHILLIPS, WILLIAM T.;KLIPPER, ROBERT W.;TIMMONS, JAMES H.;RUDOLPH, ALAN S. |
分类号 |
A61K51/12;(IPC1-7):A61K51/12 |
主分类号 |
A61K51/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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