摘要 |
Benzenesulfonamides of formula (I), in which W is OR1, NR2OR1, NRARB, NR2NRARB, or NR2(CH2)2-4NRARB and the other variables as de fined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer, stroke, heart failure, xenograft rejection, arthritis, cystic fibrosis, hepatomegaly, cardiomegaly, Alzheimer's disease, complications of diabetes, septic shock, and viral infection.
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申请人 |
WARNER-LAMBERT COMPANY;BARRETT, STEPHEN, DOUGLAS;TECLE, HAILE;BOOTH, RICHARD, JOHN |
发明人 |
BARRETT, STEPHEN, DOUGLAS;TECLE, HAILE;BOOTH, RICHARD, JOHN |