<p>Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HCV infection. The antigens are useful in diagnostic methods for detecting HCV infection in humans. Also disclosed are corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic peptides.</p>
申请公布号
EP0527815(B1)
申请公布日期
2000.07.19
申请号
EP19910908451
申请日期
1991.04.05
申请人
GENELABS TECHNOLOGIES, INC.
发明人
REYES, GREGORY;KIM, JUNGSUH, P.;MOECKLI, RANDOLPH;SIMONSEN, CHRISTIAN, C.