| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicine for inflammatory respiratory illness which contains vitamin D3 derivative(s) or pharmaceutically acceptable solvate(s) thereof as an active ingredient and has an effect of suppressing the neutrophile permeation. SOLUTION: This medicine is obtained by incorporating, in effective amount(s) for therapy, one or more vitamin D3 derivative(s) or pharmaceutically acceptable solvate(s) thereof selected from a group comprising (1) 1α- hydroxyvitamin D3, (2) 1α,24(R)-dihydroxyvitamin D3, (3) 1α,25-dihydroxyvitamin D3, (4) 1α,24,25-trihydroxyvitamin D3, (5) 24,24-difluoro-1α,25-dihydroxyvitamin D3, (6) 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxyvitamin D3, (7) 22-oxa-1α,25- dihydroxyvitamin D3, (8) 22-dehydro-1α,24(S)-dihydroxyvitamin D3-25,26,27-cyclopropane, (9) 20-epi-22-oxa-24a,26a,27a-trihomo-1α,25- dihydroxyvitamin D3, etc.
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