发明名称 METHOD FOR PREPARING (R)- (+) -3 {1- [2-( 4-BENZOYL- 2-(3,4-DIFLUOROPHENYL)MORPHOLIN- 2-YL)ETHYL]- 4-PHENYLPIPERIDIN -4-YL}-1,1- DIMETHYLUREA, ITS SALTS SOLVATES AND/OR HYDRATES
摘要 The invention concerns a method for preparing (R) -(+)- 3{1- [2-(4 -benzoyl- 2- (3,4-difluorophenyl)morpholin -2-yl}ethyl]- 4-phenylpiperidin- 4-yl]-1,1- dimethylurea, its salts solvates and/or hydrates, of formula (I), intermedia te compounds and succinate and fumarate of (R)- (+)-3{1- [2-(4-benzoyl- 2-(3,4- difluorophenyl)morpholin- 2-yl)ethyl]-4- phenylpiperidin-4- yl}-1,1- dimethylurea.
申请公布号 CA2351539(A1) 申请公布日期 2000.07.06
申请号 CA19992351539 申请日期 1999.12.14
申请人 SANOFI-SYNTHELABO 发明人 BURGOS, ALAIN;CABOS, CLAUDE;BONNEFOY, SABRINA;BERNON, FRANCOISE;LUCAS, ERIC;AULOMBARD, ALAIN
分类号 A61K31/5375;A61K31/5377;A61P1/00;A61P9/00;A61P11/00;A61P13/00;A61P25/00;A61P25/04;A61P25/06;A61P29/00;A61P37/00;A61P43/00;C07D265/30;C07D413/06;(IPC1-7):C07D413/06 主分类号 A61K31/5375
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