发明名称 |
NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS |
摘要 |
There is provided compounds of formula (I), wherein R<1>, Rx, Y, R<y>, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
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申请公布号 |
WO0035869(A1) |
申请公布日期 |
2000.06.22 |
申请号 |
WO1999SE02316 |
申请日期 |
1999.12.10 |
申请人 |
ASTRAZENECA AB;INGHARDT, TORD;KARLSSON, OLLE;LINSCHOTEN, MARCEL;NYSTROEM, JAN-ERIK |
发明人 |
INGHARDT, TORD;KARLSSON, OLLE;LINSCHOTEN, MARCEL;NYSTROEM, JAN-ERIK |
分类号 |
C07D205/04;A61K31/397;A61K31/40;A61K31/4025;A61P7/02;A61P43/00;C07D;C07D207/16;C07D405/02;C07D405/06;(IPC1-7):C07D207/16 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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