| 摘要 |
PROBLEM TO BE SOLVED: To obtain a vascularization inhibitor that has the vascularization inhibitory action and is useful for treatment of the diseases to which the vascularization participates, particularly diabetic retinopathy, retina vein occlusion, acoustic macula degeneration, vascularizing glaucoma and the like by using a specific cysteine derivative as an active ingredient. SOLUTION: This vascularization inhibitor contains, as an active ingredient, a compound represented by the formula (R1 and R2 are each H, a lower alkyl, a lower alkanoyl or the like; R3 and R4 are each OH, a lower alkoxy, amino or the like; A1-A3 are each a lower alkylene; (m) is 0 or 1) or its salts, typically N1-(6-aminohexyl)-N2-(2,2-dimethyl-3-mercaptopropionyl)-L-cysteine amide. A daily dose of this inhibitor is usually 0.1-5,000 mg, preferably 1-1,000 mg in a single dose or in several portions when it is orally given.
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