| 发明名称 |
Tumor suppressor merlin and antibodies thereof |
| 摘要 |
A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.
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| 申请公布号 |
US6077685(A) |
申请公布日期 |
2000.06.20 |
| 申请号 |
US19950478087 |
申请日期 |
1995.06.07 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
TROFATTER, JAMES A.;MACCOLLIN, MIA M.;GUSELLA, JAMES F. |
| 分类号 |
G01N33/53;A61K31/70;A61K38/00;A61K39/395;A61K48/00;A61P35/00;C07H21/04;C07K14/47;C07K14/82;C07K16/00;C07K16/18;C12N15/09;C12N15/12;C12P21/02;C12P21/08;G01N33/574;(IPC1-7):C07K14/82;C07K16/30 |
主分类号 |
G01N33/53 |
| 代理机构 |
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