发明名称 METHODS OF IDENTIFYING POINT MUTATIONS IN A GENOME
摘要 The invention relates to a method for identifying inherited point mutations in a targeted region of the genome in a large population of individuals and determining which inherited point mutations are deleterious, harmful or beneficial. Deleterious mutations are identified directly by a method of recognition using the set of point mutations observed in a large population of juveniles. Harmful mutations are identifed by comparison of the set of point mutation observed in a large set of juveniles and a large set of aged individuals of the same population. Beneficial mutations are similarly identified.
申请公布号 WO0034652(A2) 申请公布日期 2000.06.15
申请号 WO1999US29379 申请日期 1999.12.09
申请人 THILLY, WILLIAM, G. 发明人 THILLY, WILLIAM, G.
分类号 G01N33/50;C12M1/00;C12N15/09;C12Q1/68;(IPC1-7):F04B1/14;F04B1/12 主分类号 G01N33/50
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