发明名称 |
BENZOFURAN DERIVATIVES, THEIR PREPARATION AND USE |
摘要 |
The present invention relates to benzofuran derivatives having general Formula (I). A is selected from (1), (2), (3), (4) wherein: Z is O or S; s is 0 or 1; q is 0 or 1; R<4> is hydrogen, C1-6-alkyl, C2-6-alkenyl, C2-6-alkynyl, C1-6-alkyl-Aryl, or C1-6-alkyl-O-Aryl; D is a spacer group selected from branched or straight chain C1-6-alkylene, C2-6-alkenylene and C2-6-alkynylene; its enantiomers, and pharmaceutically acceptable acid addition salt thereof. The compounds are potently binding to the 5-HT1A receptor.
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申请公布号 |
WO0034263(A1) |
申请公布日期 |
2000.06.15 |
申请号 |
WO1999DK00676 |
申请日期 |
1999.12.03 |
申请人 |
H. LUNDBECK A/S;ANDERSEN, KIM;ROTTLAENDER, MARIO;BOEGESOE, KLAUS, PETER;PEDERSEN, HENRIK;RUHLAND, THOMAS;DANCER, ROBERT |
发明人 |
ANDERSEN, KIM;ROTTLAENDER, MARIO;BOEGESOE, KLAUS, PETER;PEDERSEN, HENRIK;RUHLAND, THOMAS;DANCER, ROBERT |
分类号 |
C07D307/87;A61K;A61K31/343;A61K31/357;A61K31/4045;A61K31/4525;A61K31/454;A61K31/4709;A61P;A61P9/00;A61P9/10;A61P25/00;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/32;C07D;C07D405/08;C07D405/12;C07D405/14;C07D407/12;C07D471/04;(IPC1-7):C07D307/87 |
主分类号 |
C07D307/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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