USE OF LONG-CHAIN N-ALKYL DERIVATIVES OF DEOXYNOJIRIMYCIN FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF GLYCOLIPID STORAGE DISEASES
摘要
A novel method is disclosed for the treatment of a patient affected with Gaucher's disease or other such glycolipid storage diseases. The method comprises administering to said patient a therapeutically effective amount of a long-chain N-alkyl derivative of deoxynojirimycin to alleviate or inhibit the glycolipid storage disease. The long-chain alkyl group has from nine to about 20 carbon atoms and preferably is nonyl or decyl.
申请公布号
WO0033843(A1)
申请公布日期
2000.06.15
申请号
WO1999US27918
申请日期
1999.12.08
申请人
G.D. SEARLE & CO.;UNIVERSITY OF OXFORD;JACOB, GARY, S.;PLATT, FRANCES, M.;BUTTERS, TERRY, D.;DWEK, RAYMOND, A.
发明人
JACOB, GARY, S.;PLATT, FRANCES, M.;BUTTERS, TERRY, D.;DWEK, RAYMOND, A.