发明名称 |
PURINES AND PYRIMIDINES LINKED TO A QUENCHER |
摘要 |
Compounds are described comprising purines substituted at the C-8 position and pyrimidines substituted at the C-4 or C-5 position with a linker and quencher. These compounds when incorporated into hairpin oligonucleotides quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide. These nucleotide-quencher compounds are also easy to incorporate into oligonucleotides using conventional, automated, oligonucleotide synthetic techniques. |
申请公布号 |
WO9964431(A3) |
申请公布日期 |
2000.06.15 |
申请号 |
WO1999US13107 |
申请日期 |
1999.06.10 |
申请人 |
INTERGEN COMPANY;NARDONE, GLENN;NAZARENKO, IRENA;BOAL, JILA |
发明人 |
NARDONE, GLENN;NAZARENKO, IRENA;BOAL, JILA |
分类号 |
C07H19/06;C07H19/10;C07H19/16;C07H19/20;C07H21/00 |
主分类号 |
C07H19/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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