| 摘要 |
<p>1-Methylcarbapenem compounds represented by general formula (I) or pharmacologically acceptable salts or derivatives thereof, exhibiting excellent antibacterial activities wherein n is 2, 3 or 4; R1 is hydrogen or C¿1?-C4 alkyl; nR?2¿s are each independently hydrogen or C¿1?-C4 alkyl; R?3¿ is hydrogen or C¿1?-C4 alkyl; and R?4¿ is hydrogen, C¿1?-C4 alkyl, substituted C1-C4 alkyl, cycloalkyl, or a group represented by the general formula: -C(=NH)R?5¿ (wherein R5 is hydrogen, C¿1?-C4 alkyl or amino).</p> |
