| 发明名称 |
PROCESS FOR THE PRODUCTION OF PAROXETINE HYDROCHLORIDE PROPAN-2-OL SOLVATE |
| 摘要 |
Crystalline paroxetine hydrochloride propan-2-ol solvate having a modified habit that is more easily desolvated to form the anhydrate is obtained by crystallising from a solution of paroxetine hydrochloride in propan-2-ol under intense insonation conditions, or in a continuous crystalliser, or which has been seeded with crystals of a paroxetine hydrochloride solvate or anhydrate, especially Form A anhydrate.
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| 申请公布号 |
WO0032597(A1) |
申请公布日期 |
2000.06.08 |
| 申请号 |
WO1999GB04000 |
申请日期 |
1999.11.30 |
| 申请人 |
SMITHKLINE BEECHAM PLC;CRAIG, ANDREW, SIMON;JONES, DAVID, ALAN |
发明人 |
CRAIG, ANDREW, SIMON;JONES, DAVID, ALAN |
| 分类号 |
A61K31/4427;A61P25/16;A61P25/24;C07D405/12;(IPC1-7):C07D405/12;A61K31/445 |
主分类号 |
A61K31/4427 |
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