| 发明名称 |
8-AZABICYCLO[3.2.1]OCT-2-ENE AND -OCTANE DERIVATIVES |
| 摘要 |
The present invention relates to novel 8-azabicyclo[3.2.1]oct-2-ene and - octane derivatives which are found to be cholinergic ligands at the nicotini c Acetyl Choline Receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neurodegeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substance s.
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| 申请公布号 |
CA2342621(A1) |
申请公布日期 |
2000.06.08 |
| 申请号 |
CA19992342621 |
申请日期 |
1999.11.26 |
| 申请人 |
NEUROSEARCH A/S |
发明人 |
PETERS, DAN;NIELSEN, SIMON FELDBAEK;OLSEN, GUNNAR M.;NIELSEN, ELSEBET OSTERGAARD |
| 分类号 |
C07D451/02;A61K31/46;A61K31/496;A61K31/498;A61K31/502;A61K31/506;A61K49/00;A61K49/04;A61K51/00;A61P1/00;A61P1/12;A61P1/14;A61P3/04;A61P5/14;A61P9/06;A61P9/10;A61P9/12;A61P11/06;A61P15/00;A61P15/06;A61P15/10;A61P17/10;A61P21/02;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P27/02;A61P31/18;A61P43/00;(IPC1-7):C07D451/02 |
主分类号 |
C07D451/02 |
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