发明名称 |
Dimer and multimer forms of single chain polypeptides |
摘要 |
The present invention discloses novel proteins which are dimers and multimers of single chain polypeptides. The single chain polypeptides having two domains derived from the immunoglobulin superfamily which are joined by a peptide linker. The dimers and multimers being formed by non-covalent linking of the single chain polypeptides.
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申请公布号 |
US6071515(A) |
申请公布日期 |
2000.06.06 |
申请号 |
US19950463903 |
申请日期 |
1995.06.05 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
MEZES, PETER S.;RICHARD, RUTH A.;AFFHOLTER, JOSEPH A.;KOTITE, NICOLAS J. |
分类号 |
A61K38/00;A61K51/10;A61P37/04;C07K16/30;C07K16/46;C12P21/08;(IPC1-7):A61K39/395;G01N33/53;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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