发明名称 |
Bisaryl compounds and cancer remedies containing the same |
摘要 |
Compounds represented by the general formula (I), and salts thereof, which have an effect of inhibiting ribonucleotide reductase to suppress the proliferation of cancer cells selectively: Ar<1>-S-R<1>-S-Ar<2> wherein R<1> is a monocyclic connecting group which has one saturated five-membered cyclic structure containing one or more nitrogen atoms as the ring-constituting atoms, or a bi- or tricyclic connecting group which has two or three saturated five- or six-membered cyclic structures and contains as the ring-constituting atoms one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; and Ar<1> and Ar<2> are each an aryl or heteroaryl group having one or more hydroxyl groups on the ring. |
申请公布号 |
AU1182300(A) |
申请公布日期 |
2000.06.05 |
申请号 |
AU20000011823 |
申请日期 |
1999.11.17 |
申请人 |
KYOWA HAKKO KOGYO CO. LTD.;FUJI PHOTO FILM CO. LTD. |
发明人 |
TATSUYA TAMAOKI;TAKESHI TAKAHASHI;TAMIO MIZUKAMI;SHUN-ICHI IKEDA;YUKO KANDA;AKIHIKO IKEGAWA;YONGZHE YAN |
分类号 |
A61P35/00;C07D207/12;C07D493/04 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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