发明名称 |
COMPOSITIONS AND METHODS FOR PRODUCING VASCULAR OCCLUSION |
摘要 |
The present invention relates generally to methods and compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents. In particular, antibodies carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then binds and activates platelets, which in turn bind and activate other platelets. This process results in the formation of a platelet-mediated thrombus-causing vessel occlusion.
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申请公布号 |
WO0029029(A1) |
申请公布日期 |
2000.05.25 |
申请号 |
WO1999IB01809 |
申请日期 |
1999.11.10 |
申请人 |
NOVOLYTICS INC.;STEWART, MICHAEL, WILLIAM;PERSON, ROLAND, HENRYK;NOUJAIM, ANTOINE |
发明人 |
STEWART, MICHAEL, WILLIAM;PERSON, ROLAND, HENRYK;NOUJAIM, ANTOINE |
分类号 |
A61K31/727;A61K31/737;A61K35/14;A61K38/00;A61K38/36;A61K38/48;A61K38/55;A61K39/395;A61K45/06;A61K47/48;A61P7/04;A61P35/00;C07K16/28;C07K16/30;(IPC1-7):A61K47/48 |
主分类号 |
A61K31/727 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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