| 发明名称 |
CRYSTALLINE (-)-6- CHLORO-4- CYCLOPROPYLETHYNYL- 4-TRIFLUOROMETHYL- 3,4-DIHYDRO- 2(1H)-QUINAZOLINONE |
| 摘要 |
The potent reverse transcriptase inhibitor (-)-6-Chloro-4-cyclopropylethynyl -4- trifluoromethyl-3,4-dihydro-2(1H)-quinazolinone is produced in solvate and crystalline form. These forms are designated Forms 1 and 2, and are characterized by x-ray powder diffraction and differential scanning calorimetry. Pharmaceutical compositions and methods are useful for the treatment of the human immunodeficiency virus (HIV).
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| 申请公布号 |
CA2345516(A1) |
申请公布日期 |
2000.05.25 |
| 申请号 |
CA19992345516 |
申请日期 |
1999.11.18 |
| 申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
PARSONS, RODNEY LAWRENCE JR.;RABEL, SHELLY R.;PATEL, MONA |
| 分类号 |
A61P31/18;C07D239/78;C07D239/80;(IPC1-7):C07D239/80;A61K31/505 |
主分类号 |
A61P31/18 |
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