| 摘要 |
A method for preparing high strength collagen material. Collagenic material is ground and acidified with acetic acid to a pH between 3 and 4 to form a collagenic paste with a collagen content of between 3 and 15 weight percent, on a dry collagen basis. The collagen is dried, preferably by freeze-drying, to form a high strength collagen material. The collagen material has sufficient strength to be suturable. The rigid collagen material may find application as a suturable hemostatic sponge, as a rigid sponge chondrocyte cell carrier, in forming cartilaginous anatomic appendages, in forming osseous grafts, in vascular and neural regeneration, and other applications where high strength collagen is useful.
|
