发明名称 |
Serinproteasevarianter med peptidligaseaktivitet |
摘要 |
The invention relates to serine protease variants derived from precursor serine proteases via recombinant and/or chemical methods to form protease variants having improved peptide ligase activity. The invention also includes novel ligation substrates which in combination with the serine protease variants and a second ligation substrate are capable of forming a ligation product. The invention also relates to methods for forming such ligation products and the products formed thereby. |
申请公布号 |
DK0542931(T3) |
申请公布日期 |
2000.05.22 |
申请号 |
DK19920903763T |
申请日期 |
1991.08.06 |
申请人 |
GENENTECH, INC. |
发明人 |
ABRAHMSEN, LARS;BURNIER, JOHN;WELLS, JAMES, A. |
分类号 |
C12N1/21;C07K14/61;C12N9/22;C12N9/54;C12N15/09;C12N15/57;C12P21/02;C12R1/07;C12R1/125;(IPC1-7):C12N15/57;C12N15/00;C12N9/56 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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