发明名称 ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE
摘要 The present invention describes the use of pyrazole or indazole derivates as activators of soluble guanylate cyclase. Some compounds disclosed are novel. All activators are vasodilators and/or inhibit platelet aggregation and are therefore useful in the treatment of peripheral vascular diseases such as hypertension, angina pectoris or atherosclerosis, or in the treatment of prevention of glaucoma, preeclampsia, Raynaud's syndrome, stroke or erectile disfunctions.
申请公布号 WO0027394(A1) 申请公布日期 2000.05.18
申请号 WO1999GB03663 申请日期 1999.11.05
申请人 UNIVERSITY COLLEGE LONDON;SELWOOD, DAVID;GLEN, ROBERT;LIU, QIAN;KLING, MARCEL;MADGE, DAVID;REYNOLDS, KAREN;WISHART, GRANT;POWELL, KEN 发明人 SELWOOD, DAVID;GLEN, ROBERT;LIU, QIAN;KLING, MARCEL;MADGE, DAVID;REYNOLDS, KAREN;WISHART, GRANT;POWELL, KEN
分类号 A61K31/415;A61K31/4155;A61K31/416;A61K31/4178;A61K31/4184;A61K31/422;A61K31/427;A61K31/428;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/5377;A61P7/02;A61P27/06;C07D231/32;C07D231/56;C07D401/04;C07D401/12;C07D405/04;C07D405/12;C07D409/06;C07D413/04;(IPC1-7):A61K31/415;A61K31/537;A61K31/443;A61K31/470;A61K31/418;A61K31/433;A61K31/417;A61P9/10;A61P9/08;C07D231/20;C07D231/22 主分类号 A61K31/415
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