发明名称 |
Enhanced activation of NK cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor |
摘要 |
An improved method for the prevention of the inactivation of natural killer (NK) cells and the enhanced activation of NK cells in the presence of monocytes using a combination of a natural killer cell activator and a compound effective to inhibit the production or release of intracellular hydrogen peroxide, or a hydrogen peroxide scavenger, is disclosed. The method is useful, for example, in the treatment of solid tumors, metastases and viral infection.
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申请公布号 |
US6063373(A) |
申请公布日期 |
2000.05.16 |
申请号 |
US19970932406 |
申请日期 |
1997.09.17 |
申请人 |
MAXIM PHARMACEUTICALS, INC. |
发明人 |
HELLSTRAND, JAN URBAN KRISTOFFER;HERMODSSON, SVANTE HERMOD |
分类号 |
A61K31/4045;A61K31/417;A61K35/14;A61K38/19;A61K38/20;A61K38/21;A61K38/44;A61K45/06;C12N5/0783;(IPC1-7):A61K45/00;C07K1/00;C07K14/00 |
主分类号 |
A61K31/4045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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