| 发明名称 |
3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors |
| 摘要 |
PCT No. PCT/CA96/00717 Sec. 371 Date Oct. 2, 1998 Sec. 102(e) Date Oct. 2, 1998 PCT Filed Oct. 29, 1996 PCT Pub. No. WO97/16435 PCT Pub. Date May 9, 1997The invention encompasses the novel compound of formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).
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| 申请公布号 |
US6057319(A) |
申请公布日期 |
2000.05.02 |
| 申请号 |
US19980068139 |
申请日期 |
1998.10.02 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
BLACK, CAMERON;LEGER, SERGE;PRASIT, PETPIBOON;WANG, ZHAOYIN;HAMEL, PIERRE;HAN, YONGXIN;HUGHES, GREGORY |
| 分类号 |
C07C323/64;C07D213/34;C07D307/30;C07D307/32;C07D307/58;C07D307/60;C07D307/62;C07D307/64;C07D307/66;C07D307/68;C07D307/94;C07D405/04;C07D405/12;C07D409/12;C07D417/12;(IPC1-7):A61K31/53;A61K31/415;C07D213/06;C07D253/08;C07D261/04 |
主分类号 |
C07C323/64 |
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