发明名称 |
Compositions and methods based upon p35, an isoform of p53 |
摘要 |
The present invention is directed to an isoform of the p53 tumor suppressor and to polynucleotides that encode this isoform. The isoform may be used as a marker to indicate that cardiac cells have experienced hypoxia, as would occur during a myocardial infarction. In addition, vectors encoding the isoform may be transfected into cells as a means of regulating proliferation. |
申请公布号 |
AU6418099(A) |
申请公布日期 |
2000.05.01 |
申请号 |
AU19990064180 |
申请日期 |
1999.10.07 |
申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
GIORGIO DELL'ACQUA;MICHAEL J. MANN;VICTOR J DZAU |
分类号 |
A61K38/00;A61K48/00;C07K14/47;C12N15/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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