摘要 |
The invention relates to methods for making arrays, to devices therefore, to the arrays to uses of the arrays and to devices therefore. In a particular aspect it relates to methods for making large numbers of arrays. In another particular aspect it relates to making arrays by repeating a cycle of exposing a substrate to array members, activating sectors of the substrate and binding the array members to the activated sectors, and then removing unbound material from the substrate. In a particularly preferred embodiment the substrate is long ribbon containing channels, successive groups of array members are introduced into the channels and the introduced array members are photochemically bound to selected sectors defined by photolithography. A particular embodiment relates to analyte-determining arrays and their uses, such as DNA arrays.
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