| 摘要 |
The instant invention provides compositions and methods for modeling post-Amadori AGE formation and the identification and characterization of effective inhibitors of post-Amadori AGE formation, and such identified inhibitor compositions. The instant invention also teaches methods to treat or prevent diabetes associated hyperlipidemia, cellular redox imbalances, hypercholesterolemia, hypertriglyceridemia, and atherosclerosis, comprising administering the compounds of the invention to a mammal in need thereof.
|
| 申请人 |
UNIVERSITY OF SOUTH CAROLINA;KANSAS UNIVERSITY MEDICAL CENTER RESEARCH INSTITUTE, INC.;BAYNES, JOHN, W.;THORPE, SUZANNE, R.;DEGENHARDT, THORSTEN, P.;KHALIFAH, RAJA, GABRIEL;HUDSON, BILLY;ALDERSON, NATHAN |
发明人 |
BAYNES, JOHN, W.;THORPE, SUZANNE, R.;DEGENHARDT, THORSTEN, P.;KHALIFAH, RAJA, GABRIEL;HUDSON, BILLY;ALDERSON, NATHAN |
