This invention relates to immunoassays for detection and differentiation of Group O human immunodeficiency virus infections, specifically to monoclonal antibodies reactive with Group O sequences useful as positive control reagents in immunoassays specifically containing Group O target antigen for improved detection of Group O antibodies from infected humans and in contaminated blood and blood products. The invention also relates to hybridoma cell lines capable of producing the HIV-1 Group O monoclonal antibodies and methods of detecting the HIV-1 Group O antigens.
申请公布号
WO0004383(A3)
申请公布日期
2000.04.27
申请号
WO1999US15469
申请日期
1999.07.09
申请人
ABBOTT LABORATORIES
发明人
SCHEFFEL, JAMES, W.;HACKETT, JOHN, R., JR.;TYNER, JOAN, D.;HICKMAN, ROBERT, K.