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发明名称 DIAMINOPROPIONIC ACID DERIVATIVES
摘要 Compounds of the formula (1a), wherein R1 is a group of the formula (2) wher e R1, R2, A, B, U, V, W, X, Y, Z, k and n have the significance given in the specification, are useful to treat rheumatoid arthritis, psoriasis, multiple sclerosis, Crohn's disease, ulcerative colitis, artherosclerosis, restenosis , pancreatitis, transplant rejection, delayed graft function and diseases of ischemia reperfusion injury, including acute myocardial infarction and stoke .
申请公布号 CA2344058(A1) 申请公布日期 2000.04.20
申请号 CA19992344058 申请日期 1999.10.12
申请人 F. HOFFMANN-LA ROCHE AG 发明人 FOTOUHI, NADER;PIETRANICO-COLE, SHERRIE LYNN;GUTHRIE, ROBERT WILLIAM;GILLESPIE, PAUL;YUN, WEIYA
分类号 C07D249/18;A61K31/198;A61K31/341;A61K31/343;A61K31/381;A61K31/382;A61K31/40;A61K31/41;A61K31/4184;A61K31/4192;A61K31/428;A61K31/433;A61K31/4406;A61K31/4409;A61K31/4427;A61K31/4433;A61K31/4453;A61K31/454;A61K31/4704;A61K31/472;A61K31/473;A61K31/496;A61K31/4965;A61K31/505;A61K31/519;A61K31/55;A61P1/04;A61P1/18;A61P9/10;A61P17/06;A61P19/02;A61P25/28;A61P29/00;C07C231/02;C07C231/12;C07C231/16;C07C233/83;C07C235/26;C07C235/34;C07C235/40;C07C235/52;C07C235/60;C07C237/12;C07C237/20;C07C237/24;C07C237/36;C07C237/42;C07C277/08;C07C279/14;C07C303/40;C07C309/65;C07C311/06;C07C311/16;C07C311/19;C07C319/20;C07C323/60;C07D207/327;C07D213/54;C07D213/70;C07D215/22;C07D217/16;C07D219/02;C07D223/12;C07D223/16;C07D235/06;C07D237/08;C07D239/26;C07D239/46;C07D241/12;C07D241/18;C07D257/06;C07D261/08;C07D277/62;C07D285/16;C07D295/14;C07D295/15;C07D307/33;C07D307/68;C07D307/81;C07D311/12;C07D311/22;C07D333/24;C07D333/38;C07D333/60;C07D335/16;C07D401/12;C07D409/12;C07D487/04;C07D495/10;C40B40/04;(IPC1-7):C07C235/52;A61P7/00;C07D209/08;A61K31/166;A61K31/33;C07D333/40;C07D213/56;C07C233/63;C07C233/78 主分类号 C07D249/18
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