PROCESS FOR THE PREPARATION OF ORAL PHARMACEUTICAL COMPOSITIONS COMPRISING BIPHOSPHONATES

摘要

The invention relates to a process for the preparation of bisphonate- containing pharmaceutical compositions for oral application, wherein the active substance is wet-granulated in manner known per se in a fluidised-bed granulator using adjuvants which have no abrasive action and wherein the wet granulate is then dried in the fluidised bed, screened through a screen havi ng a suitable mesh width and further processed by techniques known per se to fo rm pharmaceutical compositions.