发明名称 |
COMPOSITION COMPRISING RUTIN AND QUERCETIN FOR PREVENTING AND TREATING HYPERLIPIDEMIA, ARTERIOSCLEROSIS AND LIVER DISEASE |
摘要 |
PURPOSE: A pharmaceutical composition and a functional food comprising bioflavonoids are provided, for treating and preventing hyper lipidemia, arteriosclerosis and a liver disease. CONSTITUTION: The pharmaceutical composition comprises rutin, quercetin or their mixture ineffective amount; and pharmaceutically acceptable carriers. The functional food comprises 0.01-10 wt% of rutin, quercetin or their mixture. Rutin can be obtained from a fruit, a leaf, a trunk and a flower of buck wheat and be used in the form of a powder or an extract. Rutin and quercetin being bioflavonoids inhibit HMG CoA (3-hydroxy-3-methylglutaryl coenzyme) being a reduction enzyme which relates to the biosynthesis of cholesterol and ACAT (acyl CoA; cholesterol-O-acyltransferase) which transforms cholesterol into cholesteryl ester in the body. Therefore rutin and quercetin reduce the concentration of cholesterol in blood, inhibit strongly a macrophage-lipid complex from being deposited or adsorbed onto the intra trial surface, and protect a liver. |
申请公布号 |
KR20000019717(A) |
申请公布日期 |
2000.04.15 |
申请号 |
KR19980037959 |
申请日期 |
1998.09.15 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
PORK, SUNG HAE;JUNG, TAE SOOK;BAE, KI HWAN;PARK, YONG BORK;CHOI, MYUNG SOOK;MOON, SUNG SIK;KWUN, YONG KOON;LEE, EUN SOOK;LEE, JOON SUNG;HYUN, BYUNG HWA;CHOI, YANG KYOO;LEE, CHUL HO;AHN, BYUNG TAE;LEE, SAE BOM |
分类号 |
A21D2/14;A21D2/36;A21D13/00;A21D13/08;A23C9/13;A23C9/152;A23C19/093;A23F3/14;A23G1/00;A23G1/30;A23G3/00;A23G3/34;A23G4/00;A23G9/32;A23G9/44;A23G9/52;A23L1/16;A23L1/24;A23L1/30;A23L1/302;A23L1/314;A23L1/39;A23L1/48;A23L2/02;A23L2/52;A61K31/352;A61K31/70;A61K31/7042;A61K31/7048;A61K36/00;A61P3/06;A61P9/10;C07D311/30;C07H17/07;C12G3/00 |
主分类号 |
A21D2/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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