COPOLYMER 1 RELATED POLYPEPTIDES FOR USE AS MOLECULAR WEIGHTMARKERS AND FOR THERAPEUTIC USE

摘要

The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate an d other copolymers which display linear relationships between molar ellipticit y and molecular weight, and between retention time and the log of the molecula r weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can b e used for treating or preventing various immune diseases.