| 发明名称 |
SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS |
| 摘要 |
This invention provides compounds of formula (1) wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, whi ch are useful as antineoplastic agents and in the treatment of polycystic kidne y disease.
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| 申请公布号 |
CA2344169(A1) |
申请公布日期 |
2000.04.06 |
| 申请号 |
CA19992344169 |
申请日期 |
1999.09.22 |
| 申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
WISSNER, ALLAN;TSOU, HWEI-RU;BERGER, DAN MAARTEN;FLOYD, MIDDLETON BRAWNER JR.;SALVATI, MARK ERNEST;FROST, PHILIP;ZHANG, NAN;HAMANN, PHILIP ROSS |
| 分类号 |
A61K31/47;A61K31/4706;A61K31/4709;A61K31/4725;A61K31/496;A61K31/502;A61K31/506;A61K31/5377;A61K31/538;A61K31/5513;A61P13/00;A61P35/00;C07D215/54;C07D215/56;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/12;C07D413/12;C07D417/12;C07D417/14;C07D487/04;C07D491/04;C07D491/056;C07D491/10;(IPC1-7):C07D401/12;C07D215/00;C07D221/00;C07D317/00;C07D319/00 |
主分类号 |
A61K31/47 |
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