发明名称 INORGANIC COMPOUND SACCHARIDE COMPOSITION, VEHICLE, RAPIDLY DISINTEGRATING COMPRESSION MOLDED PRODUCT, AND THEIR PRODUCTION
摘要 PROBLEM TO BE SOLVED: To obtain, by spray drying a homogeneous suspension of an inorganic compound and a saccharide, an inorganic compound saccharide composition which has high fluidity and compression moldability in powder, rapidly disintegrating and/or dissolving properties when added into mouse or water in granule or tablet, and strength which does not allow disintegration during production and circulation. SOLUTION: This composition is obtained by spray drying a homogeneous suspension of (A) an inorganic compound (preferably, magnesium methasilicate aluminate, synthetic hydrotalcite, dry aluminum hydroxide gel, precipitated calcium carbonate, magnesium silicate aluminate, magnesium silicate, or the like) and (B) a saccharide (preferably, erythritol, mannitol, sorbitol, xylitol, or the like). It is preferable that the composition contains components A and B at 0.5-99.5 wt.% and 0.5-99.5 wt.%, respectively. It is preferable that the particle size of the composition is 500μm or smaller.
申请公布号 JP2000086537(A) 申请公布日期 2000.03.28
申请号 JP19980258946 申请日期 1998.09.11
申请人 FUJI CHEM IND CO LTD 发明人 YOKOI SHINICHIRO;SHISHIDO TAKESHI;TANAKA NOBUKAZU;HOTTA YOSHIHARU;CHO KIYOAKI;IKUSHIMA HEIJI
分类号 A61K47/36;(IPC1-7):A61K47/36 主分类号 A61K47/36
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