发明名称 4-quinolinemethanol derivatives as purine receptor antagonists.(ii)
摘要 Use of a compound of formula (I) as defined herein, or a pharmaceutically acceptable salt or prodrug thereof, in the manufacture of a medicament for the treatment or prevention of a disorder in which the blocking of purine receptors, particularly adenosine receptors and more particularly A2a receptors, may be beneficial, such as a movement disorder, for example, Parkinson's Disease or progressive supemuclear palsy, Huntingtons disease, multiple system atrophy, corticobasal degeneration, Wilsons disease, Hallerrorder-Spatz disease, progressive pallidal atrophy, Dopa-responsive dystonia-Parkinsonism, spasticity, Alzheimer's disease or other disorders of the basal ganglia which result in dyskinesias.
申请公布号 AU5640299(A) 申请公布日期 2000.03.27
申请号 AU19990056402 申请日期 1999.09.03
申请人 CEREBRUS PHARMACEUTICALS LIMITED 发明人 ROGER JOHN GILLESPIE;JOANNE LERPINIERE;PAUL RICHARD GILES;DAVID REGINALD ADAMS;LARS JACOB STRAY KNUTSEN;IAN ANTHONY CLIFFE
分类号 A61K31/47;A61P25/16;A61P25/24 主分类号 A61K31/47
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