发明名称 UNSATURATED HYDROXIMIC ACID DERIVATIVES AS PARP INHIBITORS
摘要 The object of the invention consists of novel unsaturated hydroximic acid derivatives, the process for their preparation and as active substance such as compounds containing pharmaceutical compositions. The novel compounds posses s valuable pharmaceutical effects, so they can be used in the treatment of states connected with energy deficiency of the cell caused by PARP inhibitio n, in diabetes complications, in oxygen deficient status of the heart and brain , in neurodegenerative diseases, in the treatment of autoimmune and/or viral diseases. In formula (I).
申请公布号 CA2342898(A1) 申请公布日期 2000.03.16
申请号 CA19992342898 申请日期 1999.09.02
申请人 N-GENE KUTATO KFT. 发明人 SUMEGI, BALAZS;LITERATI NAGY, PETER;TAKACS, KALMAN
分类号 C07C251/54;A61K31/15;A61K31/40;A61K31/4406;A61K31/4427;A61K31/4453;A61K31/472;A61K31/4725;A61K31/535;A61K31/5375;A61K31/5377;A61P3/00;A61P3/10;A61P7/00;A61P9/00;A61P25/00;A61P31/12;A61P37/02;A61P43/00;C07C249/08;C07C251/58;C07C259/14;C07D207/06;C07D211/14;C07D213/44;C07D213/54;C07D217/04;C07D265/30;C07D295/08;C07D295/088;C07D401/12;(IPC1-7):C07C251/58;A61K31/155;A61K31/444;A61K31/445 主分类号 C07C251/54
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