| 发明名称 |
CRYSTALLIZABLE FARNESYL PROTEIN TRANSFERASE COMPOSITIONS, CRYSTALS THEREBY OBTAINED AND METHODS FOR USE |
| 摘要 |
The present invention relates to crystalline compositions comprising farnesyl protein transferase-like polypeptides in complex with substrates and inhibitors. Also disclosed are crystallization conditions for these compositions and their use for structural determination of FPT:FPP/FPP analog: peptide/inhibitor complexes.
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| 申请公布号 |
WO0006748(A3) |
申请公布日期 |
2000.03.16 |
| 申请号 |
WO1999US16684 |
申请日期 |
1999.07.29 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
STRICKLAND, COREY;WU, ZHEN;WINDSOR, WILLIAM, T.;WEBER, PATRICIA, C. |
| 分类号 |
C12N9/10;C12N15/54;(IPC1-7):C12N15/54;C12N15/62 |
主分类号 |
C12N9/10 |
| 代理机构 |
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