| 发明名称 |
CRYSTALLINE MONOHYDRATES OF ENDO-2,3-DIHYDRO-N-(8-METHYL- -8-AZABICYCLO[3.2.1]OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1- -CARBOXAMIDE HYDROCHLORIDE AND OF ENDO-3-ETHYL-2,3- -DIHYDRO-N-(8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL)-2-OXO-1H- -BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| 摘要 |
<p>Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl- -8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-benzimidazole-1- -carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8- -methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-benzimidazole-1- -carboxamide hydrochloride of the formula 2b, the process for their preparation and pharmaceutical compositions containing them.</p> |
| 申请公布号 |
SK280555(B6) |
申请公布日期 |
2000.03.13 |
| 申请号 |
SK19930000226 |
申请日期 |
1993.03.22 |
| 申请人 |
BOEHRINGER INGELHEIM ITALIA SPA |
发明人 |
CEREDA ENZO;DUBINI ENRICA;EZHAYA ANTOINE;MAFFIONE GRAZIA;TURCONI MARCO |
| 分类号 |
A61K31/46;A61K31/415;A61K31/4184;A61K31/495;A61P1/00;A61P1/08;A61P25/00;A61P25/04;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/28;C07D235/32;C07D403/12;C07D451/04;C07D451/12;(IPC1-7):C07D451/04 |
主分类号 |
A61K31/46 |
| 代理机构 |
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