PROCESS FOR THE PRODUCTION OF N-PROTECTED AZETIDINE-2-CARBOXYLIC ACIDS (AzeOHs)

摘要

There is provided a process for the production of a N-protected azetidine-2-carboxylic acid, which process comprises the steps of: (a) addition of base to an aqueous solvent comprising an organic acid addition salt of an azetidine-2-carboxylic acid; and (b) addition of protecting agent to the resultant reaction mixture.