PROCESS FOR THE PREPARATION OF (2R)-PIPERIDINE DERIVATIVES

摘要

The invention relates to a method for preparing (R)-piperidine derivatives o f the general formulas (I) and (VII), where R1 is hydroxy, amino or C1-6-alkox y and R4 is hydroxy or amino. Said (R)-piperidine derivatives are obtained fro m (RS)-piperidine derivatives of the general formula (II), in which R2 is hydroxy, amino or C1-6-alkoxy, in the presence of trace elements and using micro-organisms or cell-free enzymes from said micro-organisms.