发明名称 |
Microemulsions as solid dosage forms for oral administration |
摘要 |
A microemulsion composition in the form of a free-flowing, compressible powder, comprises an admixture of a drug-containing oil-in-water microemulsion and a solid particle adsorbent. The drug-containing oil-in-water microemulsion comprises a oil-soluble drug, and the drug-containing microemulsion is adsorbed onto the solid particle adsorbent and forms a free-flowing, compressible powder. The composition and dosage forms of the present invention improve the bioavailability of a wide range of drugs that are known are suspected of having poor bioavailability by the utilization of several different mechanisms. |
申请公布号 |
AU5486899(A) |
申请公布日期 |
2000.03.06 |
申请号 |
AU19990054868 |
申请日期 |
1999.08.13 |
申请人 |
CIMA LABS, INC. |
发明人 |
S. INDIRAN PATHER;SANGEETA V. GUPTE;RAJENDRA K. KHANKARI;JOHN HONTZ;JOSEPH R ROBINSON;JONATHAN D. EICHMAN;RAMYA KUMBALE |
分类号 |
A61K9/107;A61K9/14;A61K9/16;A61K9/18;A61K9/20;A61K9/30;A61K9/46;A61K31/13;A61K31/137;A61K31/166;A61K31/277;A61K31/501;A61K31/52;A61K31/522;A61K31/7068;A61K31/7135;A61K38/00;A61K47/04 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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