发明名称 BICYCLISCHE DIARYLHETEROCYCLEN ALS CYCLOOXYGENASE-2-INHIBITOREN
摘要 The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. <IMAGE> I The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
申请公布号 DE69514813(D1) 申请公布日期 2000.03.02
申请号 DE1995614813 申请日期 1995.08.24
申请人 MERCK FROSST CANADA & CO., HALIFAX 发明人 PRASIT, PETPIBOON;GUAY, DANIEL;WANG, ZHAOYIN;LEGER, SERGE;THERIEN, MICHEL
分类号 C07D333/52;A61K31/12;A61K31/38;A61K31/381;A61K31/40;A61K31/425;A61P1/04;A61P7/06;A61P11/00;A61P13/02;A61P15/00;A61P25/28;A61P29/00;A61P43/00;C07C311/15;C07C317/14;C07D209/10;C07D307/79;C07D333/18;C07D409/04;C07D413/04;C07D417/04;C07D493/04;C07D495/04;(IPC1-7):C07D333/54;A61K31/44;C07D333/56;C07D491/04 主分类号 C07D333/52
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