COLD-SHOCK REGULATORY ELEMENTS, CONSTRUCTS THEREOF, AND METHODS OF USE
摘要
Regulatory elements of the 5'UTR of cold-shock inducible genes are disclosed. The elements prolong the expression of cold-shock inducible genes under conditions that elicit the cold-shock response in a bacterium, repress the expression of the cold-shock inducible genes under physiological conditions, or enhance the translation of cold-shock inducible genes under conditions that elicit a cold-shock response in bacteria. Vectors incorporating these elements are also disclosed as well as methods for expressing proteins.
申请公布号
WO0011148(A2)
申请公布日期
2000.03.02
申请号
WO1999US19030
申请日期
1999.08.20
申请人
THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY;YAMANAKA, KUNITOSHI;FANG, LI;JIANG, WEINING;MITTA, MASANORI;INOUYE, MASAYORI;ETCHEGARAY, JEAN-PIERRE