| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new polynucleotide having high homology to a nucleic acid encoding HFGAN72X polypeptide of a specific amino acid sequence in its whole length, useful for preventing infectious disease, tumor, acute cardiac insufficiency, cardiac infarction, asthma, etc. SOLUTION: This new isolated polynucleotide has a nucleotide sequence having at least 80% homology to a nucleotide sequence encoding a polypeptide of G-protein binding receptor (HFGAN72X) of the formula in its whole length or a nucleotide sequence complementary to the nucleotide sequence and is useful for preventing infectious diseases with bacteria fungi, protozoa and viruses, pain, tumor, dietary negativism, hyperphagia, asthma Parkinson's disease acute cardiac insufficiency, hypotension, hypertension, occlusal urine, osteoporosis, angina pectoris, cardiac infarction, ulcer, allergy, schizophrenia, etc. The polynucleotide is obtained by using a standard cloning and screening by an EST analysis from a cDNA library derived from human fetal brain, etc. |
