NOVEL ORPHAN CYTOKINE RECEPTORS

摘要

The present invention provides for nucleic acid sequences that encode novel mammalian receptor polypeptides, designated HUMAN OCR10 and HUMAN OCR10-A. The invention also provides assay systems that may be used to detect and/or measure ligands that bind the HUMAN OCR10 or the HUMAN OCR10-A gene product. The present invention also provides for diagnostic and therapeutic methods based on the interaction between HUMAN OCR10 or HUMAN OCR10-A and agents that initiate signal transduction through binding to HUMAN OCR10 or HUMAN OCR10-A.