Herstellung alkylierter Nucleosid-3'-Phosphate

摘要

The invention concerns a process for producing an alkylated nucleoside-3'-phosphate having a nucleobase, a pentose and a phosphate group, consisting of the following steps: (a) reaction of nucleoside-3'-phophate having protecting groups with an alkylating substance and (b) splitting off of the protecting groups. Furthermore, the invention concerns alkylated nucleoside-3'-phosphates as well as their use in tumour therapy and as a comparison substance in the <32>P-post-labelling process.