发明名称 |
TREATMENT OF REWARD DEFICIENCY SYNDROME |
摘要 |
<p>Enhancement of attentional processing is attained by administration of an endorphinase inhibitor or enkephalinase inhibitor and optionally, a dopamine precursor, or a serotonin precursor, a GABA precursor, or an endorphin or enkephalinase releaser, or certain herbal compounds including Rhodiola rosea extract (Pharmaline) and/or Huperzine. These components promote restoration of normal neurotransmitter function and the components combined enhance the release of dopamine at the nucleus accumbens and are non-addictive. Use of the dopamine precursors L-phenylalanine, or L-Tyrosine, the enkephalinase inhibitor D-phenylalanine, and/or the serotonin precursor -hydroxytryptophan and a natural acetylcholenesterase inhibitor and chromium salts (i.e. picolinate, nicotinate, etc.) is especially preferred, but not limited to assist in relieving symptoms associated with brain phenylalanine deficiency.</p> |
申请公布号 |
EP0979092(A2) |
申请公布日期 |
2000.02.16 |
申请号 |
EP19980920019 |
申请日期 |
1998.04.29 |
申请人 |
KENNETH BLUM, INC.;BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;CITY OF HOPE NATIONAL MEDICAL CENTER |
发明人 |
BLUM, KENNETH;COMINGS, DAVID, E.;IVY, JOHN, L. |
分类号 |
A61K33/24;A61K45/00;A61K31/198;A61K31/28;A61K31/465;A61K31/555;A61K36/41;A61K38/00;A61K45/06;A61K48/00;A61P3/04;A61P25/00;A61P25/18;A61P25/20;A61P25/24;A61P25/28;A61P25/30;A61P43/00;(IPC1-7):A61K33/24;A61K35/78 |
主分类号 |
A61K33/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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