| 摘要 |
PCT No. PCT/DK96/00085 Sec. 371 Date Aug. 26, 1997 Sec. 102(e) Date Aug. 26, 1997 PCT Filed Feb. 29, 1996 PCT Pub. No. WO96/26702 PCT Pub. Date Sep. 6, 1996A kit for mixing comprises a housing accommodating an ampoule containing a solid and a container containing a solvent which is either pre-pressurized or which may be pressurized when it is desired to mix to the liquid and solid components. A needle unit comprises a first needle, the opposite ends of which pierce rubber membranes closing the ampoule and the container, to establish a transport channel through which pressurized solvent flows from the container to the ampoule. The ampoule is vented through a second needle inserted through the membrane of the ampoule and provided with a micro-filter. In one embodiment, the needle unit is displaceable to cause the ends of the needles to pierce the respective membranes, and locked in place by a spring biased locking mechanism. A branch passage from the needle is connected to a cylinder containing a piston coupled to the locking mechanism. When the ampoule is full, pressure in the branch passage will rise, actuating the piston and releasing the locking mechanism. In an alternative embodiment, the needle mechanism is stationary, and the ampoule and container are moved into engagement with the respective needle ends.
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